Congenital adrenal hyperplasia (https://homosaurus.org/v3/homoit0000301)
| Congenital adrenal hyperplasia |
English
|
- Congenital adrenal hyperplasia (CAH) is a group of different but related genetic variations that affect the enzymes that allow the adrenal glands to make hormones that regulate the body’s functions. People with CAH do not consistently produce the amount of cortisol or aldosterone they need, but they may naturally produce higher-than-typical levels of androgens such as testosterone to help the body compensate. Someone with CAH can be born with XX or XY chromosomes. People with CAH and XY chromosomes are usually not considered to have a variation in sex characteristics since an increased amount of androgens will not cause the development of any characteristics that are not considered typical for people assigned male at birth. In people with XX chromosomes and CAH, the increase in androgen production can result in genital differences such as a larger-than-typical clitoris, fused labia, and the fusion of the urethra and vaginal canal to form a single opening. They may also develop some characteristics like body and facial hair or increased muscle mass during childhood or puberty.
- Term updated in collaboration with interACT: Advocates for Intersex Youth, 2022-2023.
- Revised during an extended collaboration with interACT: Advocates for Intersex Youth, 2022-2023.
- http://homosaurus.org/v2/congenitalAdrenalHyperplasia
- http://id.loc.gov/authorities/subjects/sh85001014
Hierarchy Display:
Congenital adrenal hyperplasia
Other Formats: N-Triples, JSON-LD, Extended JSON, TTL, XML, MARC XML
Temporary Experimental Formats (includes language identifiers): N-Triples, JSON-LD, TTL