00596nz a2200217n 4500 230628|||anznnbab||||||||||||||a|||||||d homoit0002833 https://homosaurus.org/v3/homoit0002833 homoit De la Chapelle syndrome XX male syndrome Intersex variations https://homosaurus.org/v3/homoit0000669 De la Chapelle syndrome causes people with XX chromosomes to be born with a penis and testes. This usually happens because a particular gene typically seen on Y chromosomes (known as the SRY gene) ends up on one of their X chromosomes and causes their genitals and internal reproductive organs to develop as they typically would in someone with XY chromosomes. People with de la Chapelle might have testes that are smaller than typical or that are undescended, and they are often infertile. In adolescence, they may experience breast growth, and they might not develop the characteristics that are usually associated with a typical testosterone puberty.