Chimerism (https://en.homosaurus.org/v3/homoit0002826)




Identifier
homoit0002826
Preferred Label
Chimerism
English
Description
Term used to describe the variation in which a person is born with two or more different sets of DNA. This can occur when multiple zygotes (such as fraternal twins) combine and develop into one fetus. Sex-chromosome discordant chimerism occurs when at least one embryo with XX chromosomes fuses with at least one embryo with XY chromosomes. A person who develops this way would have sets of both XX and XY chromosomes, or a chromosome pattern of 46XX/46XY, and could have a wide variety of different possible sex characteristics. Many people with chimerism and XX/XY chromosomes have both ovarian and testicular tissue, while others have only testes or only ovaries, and still others have gonadal dysgenesis. Some have noticeable genital differences and others do not.
English
Contributors
Developed during an extended collaboration with interACT: Advocates for Intersex Youth, 2022-2023.
English
Issued (Created)
2023-06-28 15:53:53 UTC
Modified
2025-02-23 07:12:55 UTC
Broader
Intersex variations [homoit0000669]
LCSH Close Match
Chimerism [http://id.loc.gov/authorities/subjects/sh2011001809]

Hierarchy Display

Intersex variations
Chimerism


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