Leydig cell hypoplasia (https://homosaurus.org/v3/homoit0002863)




Identifier
homoit0002863
Preferred Label
Leydig cell hypoplasia
English
Alternative Label
LCH
English
Description
People with Leydig cell hypoplasia (LCH) have XY chromosomes and a genetic insensitivity to luteinizing hormone. LCH can be either complete (known as LCH Type 1) or partial (known as LCH Type 2). Luteinizing hormone is typically responsible for the development of Leydig cells in the testicles and for signaling for those cells to produce androgens like testosterone. Someone with LCH will develop few or no Leydig cells and therefore will produce less testosterone than is typical.
English
Contributors
Developed during an extended collaboration with interACT: Advocates for Intersex Youth, 2022-2023.
English
Issued (Created)
2023-06-28 18:13:33 UTC
Modified
2023-06-28 18:13:33 UTC
Broader
Intersex variations [homoit0000669]
Narrower
Type 1 Leydig cell hypoplasia [homoit0002879]
Type 2 Leydig cell hypoplasia [homoit0002881]

Hierarchy Display

Intersex variations
Leydig cell hypoplasia
Type 1 Leydig cell hypoplasia
Type 2 Leydig cell hypoplasia


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